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1

Synthesis and hybridization properties of polyamide based nucleic acid analogues incorporating pyrrolidine-derived nucleoamino acids

Karl-Heinz Altmann, Dieter Hüsken, Bernard Cuenoud, Carlos Garcı́a-Echeverrı́a

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2000

Language:

english

File:

PDF, 153 KB

english, 2000

2

Structure-based design and synthesis of phosphinate isosteres of phosphotyrosine for incorporation in Grb2-SH2 domain inhibitors. Part 2

Clive V Walker, Giorgio Caravatti, Alastair A Denholm, John Egerton, Alex Faessler, Pascal Furet, Carlos Garcı́a-Echeverrı́a, Brigitte Gay, Ed Irving, Ken Jones, Amanda Lambert, Neil J Press, John Woo

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2000

Language:

english

File:

PDF, 172 KB

english, 2000

3

Structure-based design and synthesis of phosphinate isosteres of phosphotyrosine for incorporation in Grb2-SH2 domain inhibitors. Part 1

Pascal Furet, Giorgio Caravatti, Alastair A Denholm, Alex Faessler, Heinz Fretz, Carlos Garcı́a-Echeverrı́a, Brigitte Gay, Ed Irving, Neil J Press, Joseph Rahuel, Joseph Schoepfer, Clive V Walker

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2000

Language:

english

File:

PDF, 240 KB

english, 2000

4

Modeling of the Binding Mode of a Non-covalent Inhibitor of the 20S Proteasome. Application to Structure-Based Analogue Design

Pascal Furet, Patricia Imbach, Peter Fürst, Marc Lang, Maria Noorani, Johann Zimmermann, Carlos Garcı́a-Echeverrı́a

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2001

Language:

english

File:

PDF, 1.77 MB

english, 2001

5

A new Antennapedia-derived vector for intracellular delivery of exogenous compounds

C Garcı́a-Echeverrı́a, L Jiang, T.M Ramsey, S.K Sharma, Y.-N.P Chen

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2001

Language:

english

File:

PDF, 636 KB

english, 2001

6

Coupling of the antennapedia third helix to a potent antagonist of the p53/hdm2 protein–protein interaction

Carlos Garcı́a-Echeverrı́a, Pascal Furet, Patrick Chène

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2001

Language:

english

File:

PDF, 117 KB

english, 2001

7

Structure-Based optimisation of 2-aminobenzylstatine derivatives: potent and selective inhibitors of the chymotrypsin-Like activity of the human 20S proteasome

Pascal Furet, Patricia Imbach, Peter Fuerst, Marc Lang, Maria Noorani, Johann Zimmermann, Carlos Garcı́a-Echeverrı́a

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2002

Language:

english

File:

PDF, 175 KB

english, 2002

8

β-Homolysine Oligomers: A New Class of Trojan Carriers

C Garcı́a-Echeverrı́a, Stephan Ruetz

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2003

Language:

english

File:

PDF, 243 KB

english, 2003

9

A New Structural Class of Selective and Non-covalent Inhibitors of the Chymotrypsin-like Activity of the 20S Proteasome

C Garcı́a-Echeverrı́a, P Imbach, D France, P Fürst, M Lang, M Noorani, D Scholz, J Zimmermann, P Furet

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2001

Language:

english

File:

PDF, 121 KB

english, 2001

10

In vivo antitumor activity of NVP-AEW541—A novel, potent, and selective inhibitor of the IGF-IR kinase

Carlos Garcı́a-Echeverrı́a, Mark A Pearson, Andreas Marti, Thomas Meyer, Juergen Mestan, Johann Zimmermann, Jiaping Gao, Josef Brueggen, Hans-Georg Capraro, Robert Cozens, Dean B Evans, Doriano Fabbro

Journal:

Year:

2004

Language:

english

File:

PDF, 201 KB

english, 2004

11

Mechanical Effects on the Kinetics of the HIV Proteinase Deactivation

Petr Kuzmič, Anne G. Peranteau, Carlos Garcı&amp, #x0301, a-Echeverrı&amp, #x0301, a, Daniel H. Rich

Journal:

Biochemical and Biophysical Research Communications

Year:

1996

Language:

english

File:

PDF, 85 KB

english, 1996

12

Structural basis for the high affinity of amino-aromatic SH2 phosphopeptide ligands

Joseph Rahuel, Carlos Garcı́a-Echeverrı́a, Pascal Furet, André Strauss, Giorgio Caravatti, Heinz Fretz, Joseph Schoepfer, Brigitte Gay

Journal:

Journal of Molecular Biology

Year:

1998

Language:

english

File:

PDF, 1.29 MB

english, 1998

13

A small synthetic peptide, which inhibits the p53-hdm2 interaction, stimulates the p53 pathway in tumour cell lines

Patrick Chène, Jean Fuchs, Jacqueline Bohn, Carlos Garcı́a-Echeverrı́a, Pascal Furet, Doriano Fabbro

Journal:

Journal of Molecular Biology

Year:

2000

Language:

english

File:

PDF, 286 KB

english, 2000